Relationships Between the Release and Tissue Depletion of Norepinephrine from the Heart by Guanethidine and Reserpine

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Relationships between the release and tissue depletion of norepinephrine from the heart by guanethidine and reserpine.

• Although depletion of myoeardial norepinephrine stores has been noted following the administration of guanethidine' and reserpine,the mechanism by which this depletion occurs has not been defined. The intravenous administration of guanethidine has been shown to result in a transient sympathomimetie response, and it has been suggested that this may result from the release of norepinephrine fro...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1963

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.12.3.256